Project name: “Development and approbation of computing algorithms for qualification and quantification of ischemic heart diseases”.

This work is made under CRDF grant in cooperation with CardioMag Imaging Inc. CardioMag Imaging, Inc. (CMI) is a privately held medical device company founded in 1999 and is engaged in the development and commercialization of a unique kind of cardiac diagnostic device known as MagnetoCardioGraphs (MCG). The device the company has developed consists of the integration of highly sophisticated proprietary sensors, electronics, and software.

Responsibilities: Research and Development:

       Creation of magnetometric systems based on Superconducting Quantum Interference Devices (SQUID) with unique sensitivity and precision have stimulated investigations in tasks of space analysis of weak magnetic fields. At the SQUID’s level of sensitivity almost any body possesses certain magnetism, e.g. bodies containing ferrous alloys which are located in the earth’s magnetic field, ore deposits, the sunken ships, the automotive materiel, etc.

3D body model and mesh
Mesh for the whole structure (including body, heart and gradiometers)
Magnetic and electric dipoles

       The essence of such kind of problems is concluded in processing the measurement results having the goal to obtain certain information about the field’s source (e.g. its space location and magnetic/electric moment).
       At present investigations of the magnetic fields originating from the biological sources (biomagnetism) are the most successful. Modern SQUID-gradiometers and magnetometers permit to register weak magnetic fields which are created by the human heart, brain, muscles. However it is a technical part of a problem which is connected with the field’s parameters registration. Interpretation of the measured data, which is the other part of the problem, requires developing methods and algorithms that permit to retrieve information about sources from the measured fields and make it suitable for further analysis.


Results:

       A new techniques for solving a two-dipole inverse problem of magnetostatic was proposed. C++ code as dynamically link library was developed and has been implemented into the CMI-2409 MCG system that has been manufactured by CardioMag Inc.